Table 1 Characterization of the rabbit model
Group | Weight gain (kg) | SBP (mmHg) | Basal glucose (mg/dl) | Cholesterol (mg/dl) | Triglycerides (mg/dl) | HDL (mg/dl) | CRP (μg/ml) |
|---|---|---|---|---|---|---|---|
Control (n = 10) | 1.9 (1.7–2.0) | 100 (93–107) | 109 (101–116) | 32.2 (8.9–55.5) | 48 (32–64) | 11.1 (8.6–13.6) | 15.95 (8.2–23.7) |
HFD (n = 6) | 1.5* (1.1–1.7) | 103 (87–119) | 105 (98–112) | 1876* (1139–2613) | 253* (4–502) | 12.5 (6.9–18.1) | 39.14 (1–77.3) |
OA (n = 9) | 1.5* (1.2–1.8) | 108 (96–119) | 105 (94–115) | 28.3 (18.2–38.4) | 67.3 (40–95) | 13.8 (10.2–17.3) | 6.9 (3.8–10.0) |
OA-HFD (n = 8) | 0.7* (-0.12–1.6) | 106 (96–117) | 104 (98–111) | 2050* (1587–2514) | 290* (99–480) | 15.6 (11.0–20.3) | 18.1 (5.5–30.7) |