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Table 1 Characterization of the rabbit model

From: Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis

Group Weight gain (kg) SBP (mmHg) Basal glucose (mg/dl) Cholesterol (mg/dl) Triglycerides (mg/dl) HDL (mg/dl) CRP (μg/ml)
Control (n = 10) 1.9 (1.7–2.0) 100 (93–107) 109 (101–116) 32.2 (8.9–55.5) 48 (32–64) 11.1 (8.6–13.6) 15.95 (8.2–23.7)
HFD (n = 6) 1.5* (1.1–1.7) 103 (87–119) 105 (98–112) 1876* (1139–2613) 253* (4–502) 12.5 (6.9–18.1) 39.14 (1–77.3)
OA (n = 9) 1.5* (1.2–1.8) 108 (96–119) 105 (94–115) 28.3 (18.2–38.4) 67.3 (40–95) 13.8 (10.2–17.3) 6.9 (3.8–10.0)
OA-HFD (n = 8) 0.7* (-0.12–1.6) 106 (96–117) 104 (98–111) 2050* (1587–2514) 290* (99–480) 15.6 (11.0–20.3) 18.1 (5.5–30.7)
  1. Measures were obtained from serum or plasma samples taken just before animals were killed. Values represent mean with 95% confidence interval
  2. HFD high-fat diet, OA osteoarthritis, SBP systolic blood pressure, HDL high-density lipoprotein, CRP C-reactive protein
  3. *P < 0.05 vs. Control