2002 AECG criteria | 2016 ACR/EULAR criteria | ||
---|---|---|---|
Weight | |||
Items | 1. Ocular dryness symptoms 2. Oral dryness symptoms 3. Ocular signs: Schirmer’s test ≤ 5 mm/5 min or van Bijsterveld score ≥ 4 4. Focus score ≥ 1 foci/4 mm2 on minor salivary gland biopsy 5. Salivary gland involvement: unstimulated whole salivary flow ≤ 0.1 mL/min 6. Positive anti-SSA or SSB antibodies | 1. Labial salivary gland with focal lymphocytic sialadenitis and focus score of ≥ 1 foci/4 mm2 | 3 |
2. Anti-SSA/Ro-positive | 3 | ||
3. Ocular Staining Score ≥ 5 (or van Bijsterveld score ≥ 4) in at least one eye | 1 | ||
4. Schirmer’s test ≤ 5 mm/5 min in at least one eye | 1 | ||
5. Unstimulated whole saliva flow rate ≤ 0.1 mL/min | 1 | ||
Rules for classification | − Absence of exclusion criteriaa − Presence of any 4 of the 6 items with at least item 4 or 6, or − presence of any 3 of the 4 objective items (3, 4, 5, and 6) | Applies to any individual | |
− who meets the inclusion criteriab with at least one symptom of ocular or oral dryness or ESSDAI ≥ 1 − does not have any of the conditions listed as exclusion criteriac − and has a score of ≥ 4 when the weights from the 5 criteria items are summed |