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Table 2 Comparison of patients meeting 2016 ACR/EULAR criteria and/or 2002 AECG criteria

From: Comparison of 2002 AECG and 2016 ACR/EULAR classification criteria and added value of salivary gland ultrasonography in a patient cohort with suspected primary Sjögren’s syndrome

  Patients fulfilling both sets of criteria n = 114 Patients fulfilling ACR/EULAR set of criteria only n = 11 Patients fulfilling neither set of criteria n = 165 p value*
Age (years, mean ± SD) 56.6 ± 13.7 53.6 ± 16.2 55.0 ± 12.6 0.56
Symptom duration (years, mean ± SD) 6.6 ± 7.1 5.5 ± 6.7 5.6 ± 6.2 0.46
Female, n (%) 106 (93) 11 (100) 150 (91) 1
Xerophthalmiaa, n (%) 110 (97) 2 (18) 141 (86) < 0.01
Xerostomiaa, n (%) 111 (97) 6 (55) 144 (87) < 0.01
ESSDAI (mean ± SD) 4.8 ± 5.5 4.6 ± 3.2 3. 8 ± 4.8 0.58
ESSDAI ≥ 1, n (%) 98 (86) 10 (91) 115 (70) 1.00
Only sicca, n (%) 16 (14) 1 (9) 52 (32) 1.00
Only ESSDAI, n (%) 1 (1) 3 (27) 6 (4) < 0.01
Schirmer’s test ≤ 5 mm/5 min, n (%) 70/110 (64) 4 (36) 47/154 (31) 0.18
VB ≥ 4, n (%) 24/80 (30) 2/4 (50) 12/85 (14) 0.58
UWSF ≤ 0.1 mL/min, n (%) 73/103 (71) 2 (18) 56/152 (37) < 0.01
Abnormal SGB, n (%) 93/112 (83) 10 (91) 22/159 (14) 0.69
Anti-SSA and/or SSB positivity, n (%) 77 (68) 5 (46) 6 (4) 0.14
Anti-SSA, n (%) 75 (66) 5 (46) 5 (3) 0.18
ANA ≥ 1:320, n (%) 83 (73) 8 (73) 55 (33) 1.00
RF positivity, n (%) 51/112 (46) 4 (36) 18/165 (11) 0.75
IgG (g/L, mean ± SD) 14.5 ± 7.9 14. 7 ± 5.1 10. 5 ± 3.5 0.49
SGUS score ≥ 2, n (%) 61/105 (58) 4/9 (44) 17/141 (12) 0.50
Physician diagnosis of pSS, n (%) 111 (97) 7 (64) 17 (10) < 0.01
  1. ACR American College of Rheumatology, AECG American-European Consensus Group, ESSDAI EULAR SS Disease Activity Index, Anti-SSA anti-Sjögren's-syndrome-related antigen A, VB van Bijsterveld score, UWSF unstimulated whole salivary flow, SGB salivary gland biopsy, ANA antinuclear antibodies, RF rheumatoid factor, SGUS salivary gland ultrasonography, pSS, primary Sjögren’s syndrome
  2. *Comparison of patients fulfilling both criteria sets and of patients fulfilling only the ACR/EULAR criteria set
  3. aSubjective complaints by the patients