Fig. 1From: Patients and surgeons provide endorsement of core domains for total joint replacement clinical trialsRevised core domain set for total joint replacement clinical trials. The three layers of the “onion” represent the six core domains in the center (inner circle), which must be measured in every total joint replacement clinical trial; the middle layer (outer circle), consisting of the domains cost and patient participation in work and social activities; and the outermost layer (research agenda), which includes domains of range of motion and the time to recovery and rehabilitationBack to article page