Fig. 3
From: Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models
Atsttrin is therapeutic in the noninvasive rat OA model. a Safranin O- stained sections of the rat knee joint collected 8 weeks after induction of the noninvasive rat OA model. b OARSI score-based Safranin O-stained. c Proteoglycan loss score on the basis of Safranin O staining. Each group composed of six rats. ***p < 0.001 versus PBS-treated group. OARSI Osteoarthritis Research Society International, PBS phosphate-buffered saline