From: Factors associated with the 6-minute walk distance in patients with systemic sclerosis
 | β | (95% CI) | p |
---|---|---|---|
Male (vs female) | 58.9 | (22.6; 95.2) | 0.002 |
Age (per 1-year increment) | –2.8 | (–3.9; –1.7) | <10–3 |
Disease duration since diagnosis (per 1-year increment) | –0.7 | (–2.5; 1.0) | 0.42 |
BMI (per 1-kg/m2 increment) | –2.7 | (–5.1; –0.2) | 0.03 |
Smoking history (vs no history) | –8.2 | (–33.9; 17.5) | 0.53 |
History of venous thrombosis (vs no history) | –10.8 | (–48.6; 26.9) | 0.57 |
History of arterial thrombosis (vs no history) | –39.6 | (–77.9; –1.4) | 0.04 |
dcSSc (vs lcSSc) | –22.7 | (–57.6; 12.2) | 0.20 |
PAH (vs no PAH) | –79.2 | (–129.7; –28.8) | 0.002 |
ILD (vs no ILD) | Â | Â | 0.15 |
 Limited ILD | 22.0 | (–6.9; 50.9) |  |
 Extensive ILD | –14.7 | (–55.8; 26.4) |  |
Joint symptoms (vs no symptoms) | –16.5 | (–41.6; 8.6) | 0.20 |
Muscle symptoms (vs no symptoms) | –7.5 | (–40.6; 25.7) | 0.66 |
Hemoglobin (per 1-g/dl increment) | 9.2 | (–0.8; 19.1) | 0.07 |
CRP (per 1-mg/L increment) | –4.3 | (–6.7; –1.9) | <10–3 |
Estimated GFR (per 1-ml/min/1.73 m2 increment) | 0.2 | (–0.4; 0.9) | 0.46 |
Initial HR (per 1-bpm increment) | –1.1 | (–2.2; –0.1) | 0.03 |
ΔHR (per 1-bpm increment) | 2.8 | (1.8; 3.8) | <10–6 |
LVEF (per 1% increment) | 1.2 | (–0.5; 2.9) | 0.15 |
Positive chronotropic drug intake (vs no intake) | 14.2 | (–44.3; 72.6) | 0.63 |
Negative chronotropic drug intake (vs no intake) | –25.3 | (–52.3; 1.7) | 0.07 |