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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: The effect of kidney function on the urate lowering effect and safety of increasing allopurinol above doses based on creatinine clearance: a post hoc analysis of a randomized controlled trial

Fig. 1

Mean serum urate, time course for achieving target serum urate (SU), mean percentage change in SU over the 24-month study period and mean allopurinol dose in the control/dose escalation phase(C/DE) and immediate dose escalation (DE/DE) groups by kidney function group. The vertical line represents the start of the open-label extension phase of the study. CrCL, creatinine clearance

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