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Table 2 Urine protein markers in the subjects studied

From: Urinary angiostatin, CXCL4 and VCAM-1 as biomarkers of lupus nephritis

Urine protein markers (normalized to creatinine)

Healthy controls (N = 53)

Inactive SLE (N = 80)

Active non-renal SLE (N = 67)

Active renal SLE (N = 80)

P value

Angiostatin (ng/ng)

0.26 ± 0.60

0.34 ± 0.56

1.60 ± 2.91

18.4 ± 27.1

< 0.0001a

 < 0.0001b

CXCL4 (pg/ng)

0.11 ± 0.63

0.38 ± 1.55

5.12 ± 10.4

9.11 ± 15.7

0.0031a

 < 0.0001b

VCAM-1 (pg/ng)

18.5 ± 60.8

159 ± 357

722 ± 1100

1410 ± 1310

< 0.0001a

 < 0.0001b

  1. Values are expressed as mean ± standard deviation
  2. SLE systemic lupus erythematosus, CXCL4 CXC chemokine ligand 4, VCAM-1 vascular cell adhesion molecule-1
  3. aP value for active renal vs active non-renal groups
  4. bP value for active SLE vs inactive SLE groups
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Arthritis Research & Therapy

ISSN: 1478-6362

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