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Table 4 Performance of the protein markers in differentiating different groups of patients with SLE

From: Urinary angiostatin, CXCL4 and VCAM-1 as biomarkers of lupus nephritis

Markers

Sensitivity

Specificity

PPV

NPV

Active renal vs active non-renal

 Angiostatin

0.80

0.82

0.84

0.77

 CXCL4

0.63

0.61

0.66

0.58

 VCAM-1

0.69

0.66

0.71

0.64

 Anti-dsDNA

0.63

0.64

0.68

0.59

 Low C3

0.61

0.66

0.68

0.59

Active vs inactive SLE

 Angiostatin

0.78

0.71

0.83

0.63

 CXCL4

0.61

0.88

0.90

0.55

 VCAM-1

0.76

0.73

0.83

0.62

 Anti-dsDNA

0.65

0.65

0.78

0.51

 C3

0.74

0.73

0.84

0.61

  1. PPV positive predictive value, NPV negative predictive value, SLE systemic lupus erythematosus, CXCL4 CXC chemokine ligand 4, VCAM-1 vascular cell adhesion molecule-1