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Table 5 Urine protein markers in 68 patients with active lupus nephritis confirmed by renal biopsy

From: Urinary angiostatin, CXCL4 and VCAM-1 as biomarkers of lupus nephritis

  ISN/RPS class III/IV ± V lupus nephritis (N = 50) ISN/RPS class I, II, V lupus nephritis (N = 18) P value
Urinary angiostatin (ng/ng) 19.0 ± 27.8 17.6 ± 23.0 0.83
Urinary CXCL4 (pg/ng) 9.95 ± 16.7 4.22 ± 7.31 0.06
Urinary VCAM-1 (pg/ng) 1330 ± 1380 1560 ± 1140 0.50
Serum anti-dsDNA (IU/ml) 254 ± 81.2 179 ± 116 0.02
Serum C3 (g/L) 0.43 ± 0.17 0.60 ± 0.26 0.02
Histological activity index 8.9 ± 3.2 1.6 ± 2.0 < 0.001
Histological chronicity index 2.5 ± 0.8 0.9 ± 1.3 0.001
Renal SLEDAI score 9.3 ± 3.1 6.4 ± 2.4 < 0.001
Urinary P/Cr 3.3 ± 2.3 4.1 ± 5.4 0.56
  1. SLEDAI systemic lupus erythematosus disease activity index, CXCL4 CXC chemokine ligand 4, VCAM-1 vascular cell adhesion molecule-1P/Cr protein-to-creatinine ratio, ISN/RPS International Society of Nephrology/Renal Pathology Society