Fig. 1From: Highly selective inhibition of Bruton’s tyrosine kinase attenuates skin and brain disease in murine lupusCutaneous lesions in MRL/lpr mice. a Macroscopic lesions were scored over the course of the experiment up until the time of sacrifice (b). c BI-BTK-treated mice had ameliorated macroscopic skin lesions as compared to control-treated mice. Three representative mice are shown from each group. Shown are the results from one experiment (BI-BTK-1, n = 12; control, n = 12) (**p < 0.01, ****p < 0.0001)Back to article page