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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: BANK1 alters B cell responses and influences the interactions between B cells and induced T regulatory cells in mice with collagen-induced arthritis

Fig. 5

Contribution of B cells from collagen-induced arthritis (CIA) mice (CIA-B cells) to induced T regulatory cells (iTregs) in vivo. a, b The percentages of CD19+ cells in the bone marrow (BM), peripheral blood, spleen and draining lymph nodes (LNs) were detected by flow cytometry 7 days after the antibody injection. c, d The percentage of foxp3+ carboxyfluorescein succinimidyl ester (CFSE)- cells in the spleen and draining LNs of CIA mice with or without B cell depletion was detected by flow cytometry 3 days after the adoptive transfer of iTregs. The results represent two independent experiments with five mice per group. Bars show the means ± SEM: **P < 0.01, ***P < 0.001 and ****P < 0.0001 for the comparisons of the indicated groups using the unpaired t test

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