From: Altered white matter microstructure in lupus patients: a diffusion tensor imaging study
Healthy controls (n = 20) | SLE patients (all) (n = 64) | p value | |
---|---|---|---|
Age | 37.3 (33.06–41.46) | 36.9 (34.8–39.10) | 0.882 |
MADRS-S | 2.85 (1.38–4.32) | 12.52 (10.18–14.85) | 0.000** |
FSS | 20.6 (17.0–24.22) | 41.0 (37.2–44.83) | 0.000** |
Cognitive domain (z score) | |||
Memory domain | 102.3 (96.8–107.7) | 95.42 (91.5–99.4) | 0.078 |
Psychomotor speed | 105.7 (100.2–111.2) | 95.94 (93.2–98.7) | 0.001** |
Reaction time | 97.5 (88.6–106.4) | 89.0 (84.1–93.9) | 0.093 |
Complex attention | 106.1(102.5–109.7) | 95.75 (89.9–101.6) | 0.055 |
Cognitive flexibility | 104.5 (98.8–110.1) | 95.2 (89.7–100.7) | 0.076 |