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Table 1 Demographics and cognitive test scores (healthy controls/SLE patients)

From: Altered white matter microstructure in lupus patients: a diffusion tensor imaging study

 

Healthy controls (n = 20)

SLE patients (all) (n = 64)

p value

Age

37.3 (33.06–41.46)

36.9 (34.8–39.10)

0.882

MADRS-S

2.85 (1.38–4.32)

12.52 (10.18–14.85)

0.000**

FSS

20.6 (17.0–24.22)

41.0 (37.2–44.83)

0.000**

Cognitive domain (z score)

 Memory domain

102.3 (96.8–107.7)

95.42 (91.5–99.4)

0.078

 Psychomotor speed

105.7 (100.2–111.2)

95.94 (93.2–98.7)

0.001**

 Reaction time

97.5 (88.6–106.4)

89.0 (84.1–93.9)

0.093

 Complex attention

106.1(102.5–109.7)

95.75 (89.9–101.6)

0.055

 Cognitive flexibility

104.5 (98.8–110.1)

95.2 (89.7–100.7)

0.076

  1. Data presented as mean (95% confidence interval). Characteristics of patients and controls in the cohort after exclusions
  2. SLE systemic lupus erythematosus, MADRS-S Montgomery Asberg Depression Rate Score Self-report, FSS Fatigue Severity Score
  3. **p < 0.01