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Table 1 Demographics and cognitive test scores (healthy controls/SLE patients)

From: Altered white matter microstructure in lupus patients: a diffusion tensor imaging study

  Healthy controls (n = 20) SLE patients (all) (n = 64) p value
Age 37.3 (33.06–41.46) 36.9 (34.8–39.10) 0.882
MADRS-S 2.85 (1.38–4.32) 12.52 (10.18–14.85) 0.000**
FSS 20.6 (17.0–24.22) 41.0 (37.2–44.83) 0.000**
Cognitive domain (z score)
 Memory domain 102.3 (96.8–107.7) 95.42 (91.5–99.4) 0.078
 Psychomotor speed 105.7 (100.2–111.2) 95.94 (93.2–98.7) 0.001**
 Reaction time 97.5 (88.6–106.4) 89.0 (84.1–93.9) 0.093
 Complex attention 106.1(102.5–109.7) 95.75 (89.9–101.6) 0.055
 Cognitive flexibility 104.5 (98.8–110.1) 95.2 (89.7–100.7) 0.076
  1. Data presented as mean (95% confidence interval). Characteristics of patients and controls in the cohort after exclusions
  2. SLE systemic lupus erythematosus, MADRS-S Montgomery Asberg Depression Rate Score Self-report, FSS Fatigue Severity Score
  3. **p < 0.01