From: Altered white matter microstructure in lupus patients: a diffusion tensor imaging study
p value | |||||
---|---|---|---|---|---|
NonNPSLE patients (n = 25) | NPSLE patients (n = 39) | HC/nonNPSLE | HC/NPSLE | NonNPSLE/NPSLE | |
Demographics | |||||
MADRS-S | 7.8 (4.9–10.7) | 15.6 (12.5–18.6) | 0.036* | 0.000** | 0.000** |
Duration | 11.2 (8.1–14.4) | 11.8 (9.1–14.5) | 0.783 | ||
SDI | 0.5 (0.1–0.9) | 0.8 (0.4–1.2) | 0.312 | ||
FSS | 38 (32–43) | 43 (38–49) | 0.000** | 0.000** | 0.140 |
SLEDAI-2k | 2 (0.9–3.1) | 2.7 (1.5–3.8) | 0.430 | ||
Age | 36.0 (32.4–39.7) | 37.5 (34.6–40.3) | 0.646 | 0.925 | 0.524 |
Daily dose of GCs | 4.6 (2.9–6.2) | 5.4 (3.7–7.0) | 0.510 | ||
Cognitive domain | |||||
Memory domain | 99 (91–105) | 93 (88–98) | 0.421 | 0.033* | 0.170 |
Psychomotor speed | 100.1 (96–105) | 93 (90–97) | 0.090 | 0.000** | 0.016** |
Reaction time | 92 (85–98) | 87(80–95) | 0.317 | 0.063 | 0.399 |
Complex attention | 106 (101–111) | 89 (81–98) | 0.997 | 0.003** | 0.001** |
Cognitive flexibility | 105 (98–112) | 89 (82–97) | 0.935 | 0.004** | 0.002** |