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Table 2 Demographics and cognitive test scores (HC/nonNPSLE/NPSLE patients)

From: Altered white matter microstructure in lupus patients: a diffusion tensor imaging study

    p value   
NonNPSLE patients (n = 25) NPSLE patients (n = 39) HC/nonNPSLE HC/NPSLE NonNPSLE/NPSLE
Demographics
 MADRS-S 7.8 (4.9–10.7) 15.6 (12.5–18.6) 0.036* 0.000** 0.000**
 Duration 11.2 (8.1–14.4) 11.8 (9.1–14.5)    0.783
 SDI 0.5 (0.1–0.9) 0.8 (0.4–1.2)    0.312
 FSS 38 (32–43) 43 (38–49) 0.000** 0.000** 0.140
 SLEDAI-2k 2 (0.9–3.1) 2.7 (1.5–3.8)    0.430
 Age 36.0 (32.4–39.7) 37.5 (34.6–40.3) 0.646 0.925 0.524
 Daily dose of GCs 4.6 (2.9–6.2) 5.4 (3.7–7.0)    0.510
Cognitive domain
 Memory domain 99 (91–105) 93 (88–98) 0.421 0.033* 0.170
 Psychomotor speed 100.1 (96–105) 93 (90–97) 0.090 0.000** 0.016**
 Reaction time 92 (85–98) 87(80–95) 0.317 0.063 0.399
 Complex attention 106 (101–111) 89 (81–98) 0.997 0.003** 0.001**
 Cognitive flexibility 105 (98–112) 89 (82–97) 0.935 0.004** 0.002**
  1. Data presented as mean (95% confidence interval). Characteristics of patients and controls in the cohort after exclusions. Healthy controls (n = 20); nonNPSLE patients (n = 25); NPSLE patients (n = 39)
  2. HC healthy controls, NPSLE neuropsychiatric systemic lupus erythematosus, MADRS-S Montgomery Asberg Depression Rate Score Self-report, SDI Systemic Lupus International Collaborating Clinical/ACR Organ Damage Index, FSS Fatigue Severity Score, SLEDAI-2k SLE Disease Activity Index-2000, GC glucocorticoids
  3. *p < 0.05
  4. **p < 0.01