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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: IL-1 family cytokines and soluble receptors in systemic lupus erythematosus

Fig. 3

Partial least squares (PLS) analysis. PLS biplots relating serological markers to (i) the European Consensus Lupus Activity Measurement (ECLAM) score (a), (ii) renal involvement (b) and (iii) haematological involvement (c). The vectors and the dots show the serological markers and the observations, respectively. Labels on vectors indicate input variables with a variable importance in protection (VIP) greater than 1.25, i.e., those variables relevant in discriminating between patients with active and inactive disease (a), patients with and without nephritis (b) and patients with and without haematological involvement (c). The near zero angle between soluble IL-1 receptor 4 (sIL-1R4) and anti-dsDNA (b), and among sIL-1R4, IL-18 and free IL-18 (c) shows the association between these variables. IL-18BP, IL-18 binding protein

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