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Table 2 Associations between demographic and clinical variables and presence of anti-PAD4 antibodies

From: Smoking is not linked to the development of anti-peptidylarginine deiminase 4 autoantibodies in rheumatoid arthritis

  Univariate Models Multivariable Model*
Variable OR (95% CI) p-value OR (95% CI) p-value
Female sex 1.1 (0.6–2.2) 0.74 0.9 (0.4–1.9) 0.74
Non-Caucasian Race 1.0 (0.5–1.9) 0.87 1.5 (0.7–3.2) 0.34
Ever Smoker 0.8 (0.5–1.4) 0.46 0.8 (0.4–1.4) 0.41
Disease duration > 10 years 3.6 (2.0–6.5) < 0.01 3.5 (1.9–6.3) < 0.01
Presence of Shared epitope 2.4 (1.3–4.3) < 0.01 2.3 (1.2–4.5) 0.02
  1. OR odds ratio, CI confidence interval; *model adjusted for disease duration, SE, race, smoking status, and sex