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Table 1 Baseline characteristics of patients and healthy controls

From: Hypogalactosylation of immunoglobulin G in rheumatoid arthritis: relationship to HLA-DRB1 shared epitope, anticitrullinated protein antibodies, rheumatoid factor, and correlation with inflammatory activity

Characteristics RA (n = 178) axSpA (n = 126) HC (n = 119)
Age, years, mean ± SD 55.0 ± 12.4 44.3 ± 8.4 55.2 ± 13.5
Female sex, n (%) 148 (78.3) 82 (65.1) 93 (78.2)
Disease duration, years, median (IQR) 5.4 (1.4–11.2) 4.5 (2.1–5.5) NA
G0/G1 ratio, median (IQR) 1.25 (1.09–1.56) 0.89 (0.79–1.09) 0.95 (0.77–1.13)
CRP, mg/L, mean ± SD 19.4 ± 30.6a 5.8 ± 10.3 NA
DAS28, mean ± SD 5.1 ± 1.4a NA NA
ACPA-positive, n (%) 96 (53.9) NA NA
RF-positive, n (%) 136 (76.4) NA NA
HLA-DRB1 SE-positive, n (%) 96 (53.9) NA NA
HLA-B27-positive, n (%) NA 88 (69.8) NA
Previous/ongoing RA therapy, n (%) 127 (71%) NA NA
  1. Abbreviations: RA Rheumatoid arthritis, axSpA Axial spondyloarthritis, HC Healthy control subjects, G0/G1 ratio Ratio of agalactosylated to monogalactosylated immunoglobulin G, CRP C-reactive protein, DAS28 Disease Activity Score in 28 joints, ACPA Anticitrullinated protein antibody, RF Rheumatoid factor, HLA Human leukocyte antigen, SE Shared epitope, NA Not applicable
  2. a Data available in 173 patients