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Table 1 Baseline characteristics of patients and healthy controls

From: Hypogalactosylation of immunoglobulin G in rheumatoid arthritis: relationship to HLA-DRB1 shared epitope, anticitrullinated protein antibodies, rheumatoid factor, and correlation with inflammatory activity

Characteristics

RA (n = 178)

axSpA (n = 126)

HC (n = 119)

Age, years, mean ± SD

55.0 ± 12.4

44.3 ± 8.4

55.2 ± 13.5

Female sex, n (%)

148 (78.3)

82 (65.1)

93 (78.2)

Disease duration, years, median (IQR)

5.4 (1.4–11.2)

4.5 (2.1–5.5)

NA

G0/G1 ratio, median (IQR)

1.25 (1.09–1.56)

0.89 (0.79–1.09)

0.95 (0.77–1.13)

CRP, mg/L, mean ± SD

19.4 ± 30.6a

5.8 ± 10.3

NA

DAS28, mean ± SD

5.1 ± 1.4a

NA

NA

ACPA-positive, n (%)

96 (53.9)

NA

NA

RF-positive, n (%)

136 (76.4)

NA

NA

HLA-DRB1 SE-positive, n (%)

96 (53.9)

NA

NA

HLA-B27-positive, n (%)

NA

88 (69.8)

NA

Previous/ongoing RA therapy, n (%)

127 (71%)

NA

NA

  1. Abbreviations: RA Rheumatoid arthritis, axSpA Axial spondyloarthritis, HC Healthy control subjects, G0/G1 ratio Ratio of agalactosylated to monogalactosylated immunoglobulin G, CRP C-reactive protein, DAS28 Disease Activity Score in 28 joints, ACPA Anticitrullinated protein antibody, RF Rheumatoid factor, HLA Human leukocyte antigen, SE Shared epitope, NA Not applicable
  2. a Data available in 173 patients