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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Antibodies against chemokine receptors CXCR3 and CXCR4 predict progressive deterioration of lung function in patients with systemic sclerosis

Fig. 4

Frequency of CXCR3-positive CD14+ monocytes among CD14+ monocytes (a) as well as CXCR3 density (b) on CD14+ monocytes show a negative correlation with the predicted percentages of forced vital capacity (FVC). (c) CXCR4 density on CD4+ T cells related to isotype controls correlated with modified Rodnan Skin Score (mRSS). Correlation between CXCR4 expressions on monocytes (MFIs) with years since diagnosis (d), start of fibrosis (e), and since first organ involvement (f, first non-Raynaud symptom). Statistical analyses were performed by Spearman’s correlation; *p ≤ 0.05. MFI median fluorescence intensity

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