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Table 1 Correlations between anti-CXCR3 and anti-CXCR4 antibody levels and lung function parameters in systemic sclerosis patients

From: Antibodies against chemokine receptors CXCR3 and CXCR4 predict progressive deterioration of lung function in patients with systemic sclerosis

Lung function parameter Anti-CXCR3 Anti-CXCR4
SRT-r p values n SRT-r p values n
VC (%) –0.50 ≤ 0.001 71 −0.43 ≤ 0.001 58
FVC (%) −0.27 ≤ 0.001 284 −0.2 ≤ 0.001 271
TLC (%) −0.25 ≤ 0.001 253 −0.21 ≤ 0.001 240
DLCO-SB (%) −0.32 ≤ 0.01 274 −0.26 ≤ 0.05 64
DLCO/VA (%) −0.20 = 0.08 245 −0.16 = 0.20 64
FEV1 (%) –0.18 ≤ 0.01 278 −0.17 ≤ 0.01 265
FEV1/VC (%) +0.25 ≤ 0.05 71 +0.2 = 0.13 58
  1. R values of Spearman’s rho (SRT-r) as well as p values are shown
  2. Vital capacity (VC), forced vital capacity (FVC), total lung capacity (TLC), the diffusing capacity for carbon monoxide (DLCO) measured by a single breath (DLCO-SB), DLCO/VA, forced expiratory volume in 1 s (FEV1), and Tiffeneau index (FEV1/VC) are given