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Table 3 Pathological feature of synovial membranes

From: Traditional Chinese medicine formula Bi-Qi capsule alleviates rheumatoid arthritis-induced inflammation, synovial hyperplasia, and cartilage destruction in rats

Group (n = 8) Neutrophil infiltration Lymphocyte infiltration Plasma cell infiltration Synovial cell proliferation Proliferation of fibrous tissue
Healthy 0 0 0 0 0
Arthritic 1.00 ± 0.46 1.63 ± 0.35 1.81 ± 0.26 1.69 ± 0.37 1.38 ± 0.44
BQ high dose 0.56 ± 0.32 1.00 ± 0.53* 1.00 ± 0.53** 1.19 ± 0.26 0.94 ± 0.42
BQ moderate dose 0.44 ± 0.32* 0.56 ± 0.32*** 0.69 ± 0.26**** 1.13 ± 0.52* 0.75 ± 0.27*, &
MTX 0.50 ± 0.38 1.06 ± 0.42 0.75 ± 0.38**** 0.94 ± 0.32** 1.31 ± 0.37
  1. Data are presented as mean ± SD
  2. BQ Bi-Qi capsule, MTX methotrexate
  3. Significant effect of treatment compared to arthritic group, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001; compared to MTX-group, &P < 0.05