|
Group (n = 8)
|
Neutrophil infiltration
|
Lymphocyte infiltration
|
Plasma cell infiltration
|
Synovial cell proliferation
|
Proliferation of fibrous tissue
|
|---|
|
Healthy
|
0
|
0
|
0
|
0
|
0
|
|
Arthritic
|
1.00 ± 0.46
|
1.63 ± 0.35
|
1.81 ± 0.26
|
1.69 ± 0.37
|
1.38 ± 0.44
|
|
BQ high dose
|
0.56 ± 0.32
|
1.00 ± 0.53*
|
1.00 ± 0.53**
|
1.19 ± 0.26
|
0.94 ± 0.42
|
|
BQ moderate dose
|
0.44 ± 0.32*
|
0.56 ± 0.32***
|
0.69 ± 0.26****
|
1.13 ± 0.52*
|
0.75 ± 0.27*, &
|
|
MTX
|
0.50 ± 0.38
|
1.06 ± 0.42
|
0.75 ± 0.38****
|
0.94 ± 0.32**
|
1.31 ± 0.37
|
- Data are presented as mean ± SD
- BQ Bi-Qi capsule, MTX methotrexate
- Significant effect of treatment compared to arthritic group, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001; compared to MTX-group, &P < 0.05
