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Table 4 Pathological features of cartilage

From: Traditional Chinese medicine formula Bi-Qi capsule alleviates rheumatoid arthritis-induced inflammation, synovial hyperplasia, and cartilage destruction in rats

Group (n = 8) Cartilage layer damage depth Cartilage surface damage range Proliferation of fibrous tissue Inflammatory cell infiltration
Healthy 0 0 0 0
Arthritic 2.38 ± 0.52 2.50 ± 0.53 2.50 ± 0.53 2.75 ± 0.46
BQ high dose 1.13 ± 0.64**** 1.13 ± 0.35**** 1.25 ± 0.46*** 2.13 ± 0.35*
BQ moderate dose 0.88 ± 0.35**** 0.75 ± 0.46**** 1.13 ± 0.35**** 1.25 ± 0.46****, &
MTX 1.13 ± 0.35**** 0.88 ± 0.64**** 1.25 ± 0.46*** 1.75 ± 0.46***
  1. Data are presented as mean ± SD
  2. BQ Bi-Qi capsule, MTX methotrexate
  3. Significant effect of treatment compared to arthritic group, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001; compared to BQ high-dose group, &P < 0.05