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Table 2 Results of univariable and multivariable Cox regression analyses of clinical baseline characteristics in relation to achievement of DMARD-free sustained remission

From: Does the presence of magnetic resonance imaging-detected osteitis at diagnosis with rheumatoid arthritis lower the risk for achieving disease-modifying antirheumatic drug-free sustained remission: results of a longitudinal study

  Univariable HR (95% CI) Multivariable HR (95% CI)a
Clinical characteristics
 Age in years 1.04 (1.02–1.07)* 1.02 (0.99–1.04)
 Female gender 0.81 (0.45–1.47)  
 Symptom duration > 12 weeks 0.83 (0.46–1.50)  
 HAQ score 1.11 (0.69–1.78)  
 68-TJC 1.02 (0.98–1.05)  
 66-SJC 1.06 (1.02–1.10)* 1.03 (0.99–1.08)
 CRP mg/L 1.01 (1.0–1.02)* 1.00 (0.99–1.01)
 ESR mm/h 1.01 (1.0–1.02)  
 ACPA-positive 0.12 (0.05–0.27)* 0.16 (0.06–0.39)*
 RF-positive 0.33 (0.18–0.61)* 0.80 (0.41–1.6)
  1. ACPA anticitrullinated protein antibodies, CI confidence interval, CRP C-reactive protein, DMARD disease-modifying antirheumatic drug, ESR erythrocyte sedimentation rate, HAQ health assessment questionnaire, HR hazard ratio, RF rheumatoid factor, SJC swollen joint count, TJC tender joint count
  2. *p < 0.05
  3. aThe multivariable model includes all variables that showed a significant association with sustained DMARD-free remission in univariable Cox regression analyses. A total of 224 patients were included in the multivariable model since data on the tested variables were incomplete for 14 patients. No statistically significant differences were present between patients with missing data and the patient included in the multivariable model (data not shown)