Fig. 1
From: Interleukin-37 is increased in adult-onset Still’s disease and associated with disease activity
The expression of interleukin (IL)-37 protein levels in patients with adult-onset Still’s disease (AOSD). a Comparison of IL-37 protein levels between patients with AOSD (n = 62) and healthy control subjects (HC) (n = 50). b Comparison of IL-37 protein levels among patients with AOSD with active and inactive disease activity (active [n = 41] versus inactive [n = 21]) as well as in HC (n = 50). c Change in IL-37 protein levels in ten patients with active AOSD according to disease activity. Serum IL-37 protein levels were determined by enzyme-linked immunosorbent assay. Each symbol represents an individual patient with AOSD and an HC. Horizontal lines indicate median values. The data represent the mean ± SD. ** P < 0.01, *** P < 0.001 by Student’s t test in (a) and (b). The Wilcoxon signed-rank test was used to perform statistical analysis in (c)