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Table 2 Correlation of serum IL-37 levels with disease activity score and laboratory values

From: Interleukin-37 is increased in adult-onset Still’s disease and associated with disease activity

Disease activity markers Correlation coefficient r (P value)
Leukocytes 0.3019 (0.018)
ESR 0.3071 (0.0161)
CRP 0.3573 (0.0047)
AST 0.1366 (0.3883)
ALT − 0.0424 (0.7562)
Ferritin 0.5303 (0.0001)
Systemic score 0.4152 (0.0008)
  1. Abbreviations: ESR Erythrocyte sedimentation rate, CRP C-reactive protein, AST Aspartate transaminase, ALT Alanine transaminase
  2. These data were analyzed using Spearman’s correlation coefficient
  3. The systemic score described by Rau et al. [39] assigns a score from 0 to 12 and adds 1 point for each of the following manifestations: fever, evanescent rashes, sore throat, arthritis, myalgia, pleuritis, pericarditis, pneumonitis, lymphadenopathy, hepatomegaly or abnormal liver function tests, elevated leukocyte count > 15,000/μl, and serum ferritin > 3000 μg/L