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Table 1 M. interosseus dorsalis manus 1 characteristics in rheumatoid arthritis and osteoarthritis patients

From: Myocellular characteristics in rheumatoid arthritis and osteoarthritis patients

  Rheumatoid arthritis (n = 5) Osteoarthritis (n = 4)
MyHC-1 (%) 74.4 ± 15.6 73.3 ± 19.8
MyHC-2A (%) 23.8 ± 13.6 23.6 ± 20.8
MyHC-2X (%) 1.8 ± 2.3 3.1 ± 3.2
CSA MyHC-1 (μm2) 2534 ± 714 1906 ± 773
CSA MyHC-2 (μm2) 4263 ± 1752* 3177 ± 1201*
MN MyHC-1 2.31 ± 0.47 1.95 ± 0.31
MN MyHC-2 3.06 ± 0.75 2.06 ± 0.66#
MND MyHC-1 (μm2) 1240 ± 389 1093 ± 323
MND MyHC-2 (μm2) 1523 ± 382 1354 ± 550
Pax7+ MyHC-1 0.038 ± 0.025 0.020 ± 0.008
Pax7+ MyHC-2 0.049 ± 0.075 0.028 ± 0.025
CD86+ MyHC-1 0.036 ± 0.019 0.034 ± 0.020
CD86+ MyHC-2 0.055 ± 0.025 0.038 ± 0.026
  1. Data are shown as mean ± SD
  2. *P < 0.05, significantly different between MyHC-1 and MyHC-2 fibers within group; #P < 0.1, tendency for a between-group difference
  3. CSA cross-sectional area, MN myonuclear number, MND myonuclear domain, MyHC myosin heavy chain