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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Phenome-wide association study identifies marked increased in burden of comorbidities in African Americans with systemic lupus erythematosus

Fig. 1

Increased comorbidities across all organ systems in African Americans with systemic lupus erythematosus (SLE) compared to Caucasians using phenome-wide association studies (PheWAS). The x axis represents the PheWAS codes that are mapped to ICD-9 codes, organized and color-coded by organ system. The y axis represents the level of significance. Each triangle represents a PheWAS code. African Americans are the reference group. Triangles pointing down represent codes more common in African Americans. Triangles pointing up represent codes more common in Caucasians. The PheWAS was adjusted for age and sex, and the horizontal red line represents the false discovery rate (FDR) of 0.05. There were 163 codes that met the FDR of 0.05. African Americans with SLE had more codes compared to Caucasians with SLE for comorbidities across all organ systems. The most significant codes for each organ system are labeled

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