Table 5 Adverse events in patients
MTX (n = 69) | TwFH (n = 69) | TwFH + MTX (n = 69) | |
|---|---|---|---|
All | 45 (65) | 33 (48) | 35 (51) |
Nausea | 18 (26) | 9 (13) | 17 (25) |
Diarrhoea | 3 (4) | 2 (3) | 1 (1) |
Abdominal discomfort | 13 (19) | 9 (13) | 11 (16) |
Liver dysfunction | 13 (19) | 5 (7) | 8 (12) |
Serious Infection | 5 (7) | 0(0) | 2 (3) |
Baldness | 3 (4) | 2 (3) | 5 (7) |
Ulcer | 8 (12) | 1 (1) | 6 (9) |
Irregular menstruation | 5 (7) | 7 (10) | 5 (7) |
Anemia | 7 (10) | 1 (1) | 6 (9) |
Leucocytopenia | 4 (6) | 2 (3) | 5 (7) |
Palpitations | 3 (4) | 0 (0) | 1 (1) |
Headache | 3 (4) | 1 (1) | 2 (3) |
Fatigue | 5 (7) | 2 (3) | 1 (1) |
Weight loss | 3 (4) | 0 (0) | 1 (1) |