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Table 1 Baseline characteristics of patients with IgG4-RD (n = 215)

From: Failure of remission induction by glucocorticoids alone or in combination with immunosuppressive agents in IgG4-related disease: a prospective study of 215 patients

Variable Value
Sex (male:female) 2.2:1
Age (years) 54 (46, 62)
Diagnosis, n (%)
 Definite 102 (47.4%)
 Probable 10 (4.7%)
 Possible 103 (47.9%)
Disease duration (months) 12 (4, 36)
IgG4-RD RI 14 (10, 18)
Allergy history, n (%) 115 (53.5%)
Number of organs involved, n (%)
 1 ~ 2 78 (36.3%)
 3 ~ 4 101 (47.0%)
  ≥ 5 36 (16.7%)
Organ involvement, n (%)
 Mikulicz’s disease 138 (64.2%)
  Dacryoadenitis 95 (44.2%)
  Sialoadenitis 124 (57.7%)
 Autoimmune pancreatitis 91 (42.3%)
 Sclerosing cholangitis 58 (27.0%)
 Retroperitoneal fibrosis 50 (23.3%)
 Lung disease 62 (28.8%)
 Kidney involvement 19 (8.8%)
 Lymphadenopathy 139 (64.7%)
 Sinusitis 62 (28.8%)
 Prostatitis 30 (14.0%)
 Skin involvement 12 (5.6%)
 Aortitis/periaortitis 12 (5.6%)
 Ophthalmic disease (except for dacryoadenitis) 7 (3.3%)
 Mediastinal fibrosis 9 (4.2%)
 Hepatopathy 6 (2.8%)
 Thyroiditis 2 (0.9%)
 Central nervous system involvement 2 (0.9%)
Laboratory tests at baseline
 Eosinophils (%) 3.2 (1.6, 6.3)
 ESR (mm/h) 25 (10, 59.5)
 CRP (mg/L) 3.78 (1.15, 10.81)
 IgG (g/L) 18.87 (15.13, 24.53)
 IgG4 (mg/L) 8960 (3500, 18,600)
 IgE (kU/L) 362.5 (132.5, 774)
  1. All the continuous non-normally distributed data are presented as median (first quartile, third quartile)
  2. IgG4-RD IgG4-related disease, RI responder index, ESR erythrocyte sedimentation rate, CRP hyper-sensitivity C-reactive protein