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Table 1 Demographic and clinical characteristics of patients with systemic sclerosis (SSc)

From: Effects of selexipag and its active metabolite in contrasting the profibrotic myofibroblast activity in cultured scleroderma skin fibroblasts

 

Sample ID

Parameters

SSc1

SSc2

SSc3

SSc4

SSc5

SSc6

Age

51

58

56

78

65

72

Sex

F

F

F

F

F

F

RP duration (months)

108

168

36

720

180

288

Disease duration (months)

108

168

24

48

36

288

Skin involvement

lcSSc

lcSSc

lcSSc

lcSSc

lcSSc

lcSSc

mRSS score

17

4

14

14

5

17

VCP pattern

Active

Active

Active

Active

Active

Active

ANA

Positive

Positive

Positive

Positive

Positive

Positive

Autoantibody

Scl70

CENP

Fibrillarin

CENP

CENP

CENP

Organ involvement

Yes (lung, esophagus)

No

No

No

No

No

Therapy

Ca2+ antagonists, ACE inhibitors, immunosuppressors, ERAs, aspirin, vitamin D

Aspirin, aminaphtone, angiotensin receptor blockers

Aminaphtone, vitamin D

Aspirin, steroids, ACE inhibitors, aminaphtone, MTX

Aspirin

Aminaphtone, vitamin D

  1. Demographic and clinical parameters of patients with SSc enrolled into the study
  2. F female, RP Raynaud’s phenomenon, lcSSc  “limited” cutaneous systemic sclerosis skin involvement, mRSS modified Rodnan skin score, VCP nailfold videocapillaroscopy, ANA anti-nuclear antibody, Scl70 anti-topoisomerase antibody, CENP anti-centromere antibody, ACE angiotensin converting enzyme, ERA endothelin receptor antagonist, MTX methotrexate