Fig. 3

Results of multivariate analysis of the lipid species data obtained from patients with polymyositis (PM)/dermatomyositis (DM) before and after immunosuppressive treatment. a Score plot from unsupervised clustering by principal component analysis (PCA). Samples from patients with PM/DM before treatment are shown as blue squares and after treatment as red triangles. b Score plot visualizing separation of the samples from patients before and after treatment based on supervised clustering (OPLS). Paired before-treatment and after-treatment samples are shown in the same color. c The corresponding loading plot obtained from OPLS. Lipids important for the separation of patients before and after treatment are highlighted in red