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Table 1 Fatty acid composition of total serum lipids from patients with polymyositis and dermatomyositis compared to healthy individuals

From: Targeted lipidomics analysis identified altered serum lipid profiles in patients with polymyositis and dermatomyositis

FA

Healthy individuals,weight %

Patients,weight %

C14:0

1.6 ± 0.8

2.1 ± 0.7

C16:0

21.6 ± 5.2

24.5 ± 3.0*

C16:1

1.8 ± 0.7

2.1 ± 0.8

C18:0

9.8 ± 1.0

8.9 ± 1.3

C18:1

24.7 ± 3.0

26.5 ± 4.6

C18:2(n-6)

27.9 ± 4.4

25.6 ± 5.1

C18:3(n-3)

1.4 ± 0.7

1.2 ± 0.5

C20:3(n-6)

1.3 ± 0.4

1.1 ± 0.5

C20:4(n-6)

5.4 ± 1.1

4.3 ± 1.3*

C20:5(n-3)

2.2 ± 1.2

1.8 ± 1.4

C22:6(n-3)

2.4 ± 0.8

1.9 ± 0.7

SFA

32.9 ± 4.9

35.5 ± 3.0

MUFA

26.5 ± 3.4

28.7 ± 5.1

PUFA

40.5 ± 5.8

35.8 ± 7.3

n-3 PUFA

5.9 ± 1.7

4.9 ± 2.0

n-6 PUFA

34.6 ± 4.9

30.9 ± 6.3

  1. Values given as mean ± SD
  2. FA fatty acids, SFA saturated fatty acids, MUFA monounsaturated fatty acids, PUFA polyunsaturated fatty acids
  3. *p < 0.05 for patients versus healthy individuals