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Table 2 Fatty acid composition of total serum lipids from patients with polymyositis and dermatomyositis before and after immunosuppressive treatment

From: Targeted lipidomics analysis identified altered serum lipid profiles in patients with polymyositis and dermatomyositis

FA

Before treatment, weight %

After treatment,weight %

C14:0

0.96 ± 0.48

1.33 ± 0.33

C16:0

22.78 ± 1.98

23.18 ± 1.60

C16:1

1.85 ± 0.84

2.06 ± 0.93

C18:0

10.76 ± 1.44

9.96 ± 1.33

C18:1

25.34 ± 3.53

24.02 ± 2.92

C18:2(n-6)

21.98 ± 3.34

23.02 ± 3.11

C18:3(n-6)

0.04 ± 0.12

0.17 ± 0.20

C18:3(n-3)

1.81 ± 1.03

2.37 ± 0.65

C20:1

0.3 ± 0.32

0.13 ± 0.26

C20:2(n-6)

0.1 ± 0.13

0.46 ± 0.37*

C20:3(n-6)

1.27 ± 0.36

1.31 ± 0.34

C20:4(n-6)

5.83 ± 1.61

4.96 ± 1.07

C20:5(n-3)

1.25 ± 0.44

1.91 ± 0.65*

C22:0

0.2 ± 0.45

0.2 ± 0.17

C22:5(n-3)

1.0 ± 0.44

1.18 ± 0.18

C22:6(n-3)

4.38 ± 1.77

3.55 ± 0.70

SFA

34.7 ± 2.6

34.9 ± 2.7

MUFA

26.4 ± 3.4

27.5 ± 4.5

PUFA

38.9 + 3.4

37.6 + 4.9

n-3 PUFA

9.0 ± 1.6

8.4 ± 1.9

n-6 PUFA

29.9 ± 2.8

29.2 ± 4.1

  1. Values given as mean ± SD
  2. FA fatty acids, SFA saturated fatty acids, MUFA monounsaturated fatty acids, PUFA polyunsaturated fatty acids
  3. *p < 0.05 for after treatment versus before treatment