|
Patients with two RA inpatient/outpatient diagnoses 7 days apart and within 12 months of each other in claims; age ≥ 18 years at first such RA diagnosis
|
49,606
|
49,606
|
|
Requiring ≥ 1 prescriptions of corresponding drugs from EHR at or after first RA diagnosis (first prescription defined as index prescription)
|
8025
|
5129
|
|
Requiring ≥ 12 months before index and ≥ 2 (for MTX) or ≥ 3 (for B/T) months after index of continuous medical and pharmacy benefits coverage (≤ 45 days of insurance gap allowed)
|
2401
|
1266
|
|
Excluding patients with filling or administration of corresponding drugs in claims during 12+ months before index
|
968
|
483
|
|
Excluding patients with RA-related hospitalizations in claims within 2 (MTX) or 3 (B/T) months after index prescription
|
955
|
476
|
|
Excluding patients with B/T fills or administration in pharmacy and medical claims during 12+ months before index (i.e., biologic naïve)
|
848
|
–
|
|
Excluding patients with ≥ 2 diagnoses of psoriasis or psoriatic arthritis, inflammatory bowel disease, ankylosing spondylitis, or cancer (excluding nonmelanoma skin cancer) in claims during 12+ months before index (final sample size)
|
763
|
434
|
