Skip to main content

Table 2 Mean change stratified by baseline PDQ group adjusted for baseline value

From: The course of pain hypersensitivity according to painDETECT in patients with rheumatoid arthritis initiating treatment: results from the prospective FRAME-cohort study

 

PDQ score < 13

PDQ score 13–18

PDQ score ≥ 19

p value

(n = 66)

(n = 23)

(n = 12)

PDQ consistency, N (%)

64 (97)

19 (83)

0 (0)

< 0.001†

Δ PDQ score

−4.10 (−5.74;-2.45)

−2.20 (− 4.64;0.25)

−5.49(−9.97;-1.02)

0.08

Δ 28 SJC

−2.71 (− 3.26;-2.17)

− 2.27 (− 3.21;-1.34)

− 2.48(− 3.77;-1.19)

0.71

Δ 28 TJC

− 4.63(− 5.67;-3.60)

−4.36(− 5.14; − 1.58)

−5.57(−7.96;-3.18)

0.28

Δ CRP, mg/mL

−6.93 (− 8.54;-5.32)

−2.81 (− 5.54;-0.08)

−6.28 (− 10.10;- 2.47)

0.04a

Δ DAS28-CRP

− 1.47 (− 1.74; − 1.20)

−0.8(− 1.27;-0.34)

−1.62 (− 2.25;-1.00)

0.03b

Δ Tender point count

−2.70 (− 3.87;-1.57)

−1.56 (− 3.48; 0.36)

− 3.83 (− 6.46;-1.20)

0.35

Δ VAS-fatigue

−18.31(− 25.55;-13.06)

−8.19 (− 17.07; 0.68)

−22.20 (− 34.48;-9.91)

0.09

Δ VAS-pain

−23.27(− 28.21;-18.33)

−12.99(− 21.40;-4.57)

−26.86 (− 38.34;-15.38)

0.07

Δ VAS-global health

−26.20(− 31.15;-21.25)

−13.49 (− 21.83;-5.15)

−31.72 (− 43.44;-20.01)

0.01b

Δ HAQ-DI

− 0.34 (− 0.44;-0.24)

− 0.15 (− 0.32; 0.02)

−0.74 (− 0.98;-0.50)

< 0.001c

Δ MDI-total

− 3.04(− 4.39;-1.68)

−2.54 (− 4.83;-0.25)

−3.68(− 6.80;-0.55)

0.84

Δ GAD10-total

−2.24 (− 3.18;-1.30)

−1.56 (− 3.15; 0.02)

−2.10 (− 4.27; 0.07)

0.76

Δ SF36-MCS

5.5 (3.34; 7.60)

3.70 (0.09; 7.31)

11.38 (6.40;16.36)

0.04c

Δ SF36-PCS

6.47 (4.39; 8.56)

4.94 (1.43; 8.44)

8.96 (3.97; 13.94)

0.42

Δ RAMRIS H synovitis

−1.69 (− 2.32;-1.07)

− 1.81(− 2.90,-0.71)

−2.47 (− 4.28;-0.66)

0.72

Δ RAMRIS H edema

−2.17 (− 4.00;-0.34)

− 0.57(− 3.80;2.66)

− 3.46 (− 8.72;1.81)

0.58

  1. Values are means (95% CI). Negative numbers indicate improvement. ANCOVA (BOCF) was used for the analyses unless otherwise indicated. †Chi-square test
  2. RAMRIS H hand (W + M). W wrist. M MCP joints
  3. (n) for RAMRIS parameters: PDQ score < 13; n = 51, PDQ score 13–18; n = 18, PDQ score > 18; n = 6. (a) No difference between PDQ score < 13 and > 18, and 13–18 and > 18. (b) No difference between PDQ score < 13 and PDQ score > 18. (c) No difference between PDQ score < 13 and 13–18
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us