| |
PDQ score < 13
|
PDQ score 13–18
|
PDQ score ≥ 19
|
p value
|
|---|
|
(n = 66)
|
(n = 23)
|
(n = 12)
|
|---|
|
PDQ consistency, N (%)
|
64 (97)
|
19 (83)
|
0 (0)
|
< 0.001†
|
|
Δ PDQ score
|
−4.10 (−5.74;-2.45)
|
−2.20 (− 4.64;0.25)
|
−5.49(−9.97;-1.02)
|
0.08
|
|
Δ 28 SJC
|
−2.71 (− 3.26;-2.17)
|
− 2.27 (− 3.21;-1.34)
|
− 2.48(− 3.77;-1.19)
|
0.71
|
|
Δ 28 TJC
|
− 4.63(− 5.67;-3.60)
|
−4.36(− 5.14; − 1.58)
|
−5.57(−7.96;-3.18)
|
0.28
|
|
Δ CRP, mg/mL
|
−6.93 (− 8.54;-5.32)
|
−2.81 (− 5.54;-0.08)
|
−6.28 (− 10.10;- 2.47)
|
0.04a
|
|
Δ DAS28-CRP
|
− 1.47 (− 1.74; − 1.20)
|
−0.8(− 1.27;-0.34)
|
−1.62 (− 2.25;-1.00)
|
0.03b
|
|
Δ Tender point count
|
−2.70 (− 3.87;-1.57)
|
−1.56 (− 3.48; 0.36)
|
− 3.83 (− 6.46;-1.20)
|
0.35
|
|
Δ VAS-fatigue
|
−18.31(− 25.55;-13.06)
|
−8.19 (− 17.07; 0.68)
|
−22.20 (− 34.48;-9.91)
|
0.09
|
|
Δ VAS-pain
|
−23.27(− 28.21;-18.33)
|
−12.99(− 21.40;-4.57)
|
−26.86 (− 38.34;-15.38)
|
0.07
|
|
Δ VAS-global health
|
−26.20(− 31.15;-21.25)
|
−13.49 (− 21.83;-5.15)
|
−31.72 (− 43.44;-20.01)
|
0.01b
|
|
Δ HAQ-DI
|
− 0.34 (− 0.44;-0.24)
|
− 0.15 (− 0.32; 0.02)
|
−0.74 (− 0.98;-0.50)
|
< 0.001c
|
|
Δ MDI-total
|
− 3.04(− 4.39;-1.68)
|
−2.54 (− 4.83;-0.25)
|
−3.68(− 6.80;-0.55)
|
0.84
|
|
Δ GAD10-total
|
−2.24 (− 3.18;-1.30)
|
−1.56 (− 3.15; 0.02)
|
−2.10 (− 4.27; 0.07)
|
0.76
|
|
Δ SF36-MCS
|
5.5 (3.34; 7.60)
|
3.70 (0.09; 7.31)
|
11.38 (6.40;16.36)
|
0.04c
|
|
Δ SF36-PCS
|
6.47 (4.39; 8.56)
|
4.94 (1.43; 8.44)
|
8.96 (3.97; 13.94)
|
0.42
|
|
Δ RAMRIS H synovitis
|
−1.69 (− 2.32;-1.07)
|
− 1.81(− 2.90,-0.71)
|
−2.47 (− 4.28;-0.66)
|
0.72
|
|
Δ RAMRIS H edema
|
−2.17 (− 4.00;-0.34)
|
− 0.57(− 3.80;2.66)
|
− 3.46 (− 8.72;1.81)
|
0.58
|
- Values are means (95% CI). Negative numbers indicate improvement. ANCOVA (BOCF) was used for the analyses unless otherwise indicated. †Chi-square test
- RAMRIS H hand (W + M). W wrist. M MCP joints
- (n) for RAMRIS parameters: PDQ score < 13; n = 51, PDQ score 13–18; n = 18, PDQ score > 18; n = 6. (a) No difference between PDQ score < 13 and > 18, and 13–18 and > 18. (b) No difference between PDQ score < 13 and PDQ score > 18. (c) No difference between PDQ score < 13 and 13–18
