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Table 3 Baseline values and mean changes (adjusted for baseline value) for the exploratory DCE-MRI variables

From: The course of pain hypersensitivity according to painDETECT in patients with rheumatoid arthritis initiating treatment: results from the prospective FRAME-cohort study

  PDQ score < 13 PDQ score 13–18 PDQ score ≥ 19 p value
Baseline values
 Nvoxel in ml wrist 13.17 (5.53–29.40) 14.78(7.22–25.84) 14.21(8.28–22.70) 0.93
 Nvoxel in ml MCP 1.65 (0.47–6.57) 3.12(0.80–9.22) 1.69(0.00–3.91) 0.56
 IRE x Nvoxel in ml wrist 0.15 (0.05–0.67) 0.25(0.04–0.67) 0.19(0.06–0.56) 0.91
 IRE x Nvoxel in ml MCP 0.02 (0.002–0.15) 0.06(0.003–0.24) 0.006(0.00–0.07) 0.31
 ME x Nvoxel in ml wrist 21.43(9.76–62.29) 26.65(10.09–56.40) 26.73(14.72–42.67) 0.92
 ME x Nvoxel in ml MCP 2.30 (0.67–14.23) 6.70(0.91–21.34) 2.46(0.00–7.42) 0.50
 IRE x ME wrist 0.02 (0.01–0.05) 0.03(0.01–0.06) 0.02(0.01–0.05) 0.87
 IRE x ME MCP 0.03 (0.01–0.09) 0.04(0.01–0.12) 0.01(0.00–0.05) 0.21
Mean changes
 Δ Nvoxel in ml wrist − 2.22 (− 4.84;0.41) − 2.47(− 6.93;1.99) − 2.87(− 10.37;4.63) 0.98
 Δ Nvoxel in ml MCP − 1.99 (− 3.02;-0.96) − 1.72(− 3.47;0.03) −0.79 (− 3.74;2.17) 0.74
 Δ IRE x Nvoxel in ml wrist −0.18(− 0.28;-0.07) −0.11(− 0.29;0.07) −0.17(− 0.46;0.13) 0.80
 Δ IRE x Nvoxel in ml MCP −0.07 (− 0.11;-0.03) −0.06(− 0.13;0.003) −0.06(− 0.17;0.06) 0.99
 Δ ME x Nvoxel in ml wrist −7.72 (− 14.69;-0.76) −5.55(− 17.37;6.27) −7.90(− 27.80;12.00) 0.95
 Δ ME x Nvoxel in ml MCP −5.17(− 7.42;-2.92) − 4.82(− 8.64;-1.00) −3.12(− 9.58;3.33) 0.84
 Δ IRE x ME wrist −0.01 (− 0.02;− 0.01) −0.01(− 0.02;0.003) -0.01(− 0.03;0.01) 0.81
 Δ IRE x ME MCP − 0.03(− 0.04;-0.02) −0.03(− 0.06;-0.01) −0.03(− 0.07;0.01) 0.96
  1. Baseline values are medians (25th, 75th percentiles)
  2. PDQ score < 13, n = 49; PDQ score 13–18, n = 17; PDQ score > 18: n = 6