|
Protocolized models
|
PDQ score < 13
|
PDQ score 13–18
|
PDQ score > 18
|
p value
|
|---|
|
Unadjusted model
|
|
ΔDAS28
|
−1.30(− 1.64;-0.97)
|
−1.17(− 1.74;-0.60)
|
− 2.08(− 3.06;-1.10)
|
0.27
|
|
ΔRAMRIS Synovitis
|
−1.68(− 2.30;-1.06)
|
−1.75(− 2.80;-0.70)
|
−2.46(− 4.25;-0.66)
|
0.72
|
|
ΔVAS pain
|
−17.57(− 24.13;-11.02)
|
− 25.45(− 36.56;-14.33)
|
−38.13(− 57.15;-19.11)
|
0.09
|
|
Adjusted
|
|
ΔDAS28
|
−1.49 (− 1.81;-1.18)
|
−1.16(− 1.70;-0.61)
|
−2.06(− 2.94;-1.17)
|
0.17
|
|
ΔRAMRIS Synovitis
|
−1.78(− 2.44;-1.26)
|
−1.72(− 2.86;-0.57)
|
−2.48(− 4.34;-0.63)
|
0.74
|
|
ΔVAS pain
|
− 19.36(− 25.89;-12.83)
|
−24.71(− 36.07;-13.35)
|
−38.04(− 56.50;-19.56)
|
0.15
|
- No interaction was found in any of the models. The protocolized unadjusted models included the baseline PDQ classification groups as a trichotomous variable and RAMRIS synovitis score for the hand. The adjusted models further included female sex, disease duration, initiation group, and DAS28-CRP as covariates
- Protocolized models, n: PDQ score < 13; n = 51, PDQ score 13–18; n = 18, PDQ score > 18; n = 6
