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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Pannus inflammation in sacroiliitis following immune pathological injury and radiological structural damage: a study of 193 patients with spondyloarthritis

Fig. 1

Pathologic features of the cartilage in sacroiliitis (hematoxylin-eosin staining (a, c-f), safranin O-fast green staining (b)). a Subchondral pannus invasion into the cartilage, accompanied with chondrocyte hypertrophy degeneration (arrow with black outline). b Pannus invasion resulted in cartilage matrix depletion (arrow with orange outline). c Neovascular formation and fibrotic cartilage (arrow with yellow outline). d Granulation tissue repaired the destroyed cartilage (arrow with blue outline). e Synovium pannus that has invaded into the cartilage surface (arrow with green outline). f Endochondral ossification (arrow with red outline)

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