Table 1 Pathological changes in different grades of sacroiliitis
Sacroiliitis < 2 (N = 271) | Sacroiliitis ≥2 (N = 115) | P | |
|---|---|---|---|
Chondrocyte degeneration, n/n* (%) | 52/234 (22.2) | 55/90 (61.1) | 0.000 |
Cartilage matrix degeneration, n/n* (%) | 103/234 (44.0) | 70/90 (77.8) | 0.000 |
Cartilage pannus invasion, n/n * (%) | 61/234 (26.1) | 52/90 (57.8) | 0.000 |
Cavity side pannus invasion, n/n * (%) | 7/234 (3.0) | 12/90 (13.3) | 0.001 |
Marrow side pannus invasion, n/n * (%) | 57/234 (24.4) | 51/90 (56.7) | 0.000 |
Endochondral ossification, n/n * (%) | 15/234 (6.4) | 25/90 (27.8) | 0.000 |
Subchondral pannus formation, n/n * (%) | 134/174 (77.0) | 70/75 (93.3) | 0.001 |
Subchondral bone disruption, n/n * (%) | 128/174 (73.6) | 69/75 (92.0) | 0.001 |
Osteoclast activation, n/n * (%) | 81/174(46.6) | 37/75 (49.3) | 0.065 |
Pathologic new bone formation, n/n * (%) | 47/174 (27.0) | 29/75 (38.7) | 0.155 |
Sequestrum, n/n * (%) | 7/174 (4.0) | 13/75 (17.3) | 0.000 |
Marrow inflammatory cell infiltration, n/n * (%) | 57/108 (52.8) | 19/54 (35.2) | 0.017 |
Synovitis, n/n * (%) | 8/27 (29.6) | 4/6 (66.7) | 0.173 |
Enthesitis, n/n * (%) | 5/31 (16.1) | 11/23 (47.8) | 0.019 |