Parameter | Control (n = 50) | HUA (n = 50) | Gout (n = 49) |
---|---|---|---|
Basic characteristics | |||
 Age (years) | 43.8 ± 11.5 | 39.08 ± 10.4* | 45.6 ± 7.3## |
 Sex (female/male) | 0/50 | 0/50 | 0/50 |
 BMI (kg/m2) | 23.4 ± 3.2 | 27.09 ± 3.0** | 26.5 ± 3.3** |
 Smoker/non-smoker | 24/26 | 22/28 | 23/26 |
 Alcohol consumption (%) | 61 | 67 | 57 |
Clinical variables | |||
 DBP (mmHg) | 78.6 ± 5.7 | 85.1 ± 11.1** | 91.8 ± 12.4**## |
 SBP (mmHg) | 114.8 ± 6.5 | 125.8 ± 14.4** | 136.3 ± 19.2**## |
 ALT(U/L) | 22.6 ± 11.3 | 43.8 ± 30.6** | 34.8 ± 18.9** |
 AST(U/L) | 20.5 ± 5.9 | 27.7 ± 14.8** | 26.8 ± 12.9** |
 Total protein (g/L) | 74.8 ± 4.3 | 75.5 ± 4.4 | 74.6 ± 4.5 |
 Albumin (g/L) | 49.4 ± 2.9 | 48.9 ± 2.2 | 47.8 ± 3.3**# |
 Globulin (g/L) | 25.4 ± 4.0 | 26.7 ± 3.5 | 26.9 ± 4.0 |
 Fasting glucose (mmol/L) | 5.0 ± 0.4 | 5.7 ± 0.7** | 6.3 ± 1.9**# |
 Urea nitrogen (mmol/L) | 5.6 ± 1.3 | 5.4 ± 1.2 | 5.5 ± 1.8 |
 Creatinine (μmol/L) | 80.6 ± 9.6 | 81.2 ± 13.9 | 91.8 ± 23.2**## |
 Uric acid (μmol/L) | 325.1 ± 60.6 | 470.6 ± 55.0** | 536.2 ± 131.4**## |
 Triglyceride (mmol/L) | 1.1 ± 0.4 | 2.3 ± 1.2** | 3.1 ± 2.1** |
 Cholesterol (mmol/L) | 4.7 ± 0.8 | 5.2 ± 0.8** | 5.4 ± 1.0** |
 HDL-cholesterol (mmol/L) | 1.4 ± 0.3 | 1.1 ± 0.2** | 1.3 ± 0.3## |
 LDL-cholesterol (mmol/L) | 2.7 ± 0.5 | 3.2 ± 0.7** | 3.0 ± 0.6* |