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Table 1 Baseline characteristics (demographic, anthropometric and clinical data) for the HUA, gout, and control groups

From: Metabolomics approach by 1H NMR spectroscopy of serum reveals progression axes for asymptomatic hyperuricemia and gout

Parameter

Control (n = 50)

HUA (n = 50)

Gout (n = 49)

Basic characteristics

 Age (years)

43.8 ± 11.5

39.08 ± 10.4*

45.6 ± 7.3##

 Sex (female/male)

0/50

0/50

0/50

 BMI (kg/m2)

23.4 ± 3.2

27.09 ± 3.0**

26.5 ± 3.3**

 Smoker/non-smoker

24/26

22/28

23/26

 Alcohol consumption (%)

61

67

57

Clinical variables

 DBP (mmHg)

78.6 ± 5.7

85.1 ± 11.1**

91.8 ± 12.4**##

 SBP (mmHg)

114.8 ± 6.5

125.8 ± 14.4**

136.3 ± 19.2**##

 ALT(U/L)

22.6 ± 11.3

43.8 ± 30.6**

34.8 ± 18.9**

 AST(U/L)

20.5 ± 5.9

27.7 ± 14.8**

26.8 ± 12.9**

 Total protein (g/L)

74.8 ± 4.3

75.5 ± 4.4

74.6 ± 4.5

 Albumin (g/L)

49.4 ± 2.9

48.9 ± 2.2

47.8 ± 3.3**#

 Globulin (g/L)

25.4 ± 4.0

26.7 ± 3.5

26.9 ± 4.0

 Fasting glucose (mmol/L)

5.0 ± 0.4

5.7 ± 0.7**

6.3 ± 1.9**#

 Urea nitrogen (mmol/L)

5.6 ± 1.3

5.4 ± 1.2

5.5 ± 1.8

 Creatinine (μmol/L)

80.6 ± 9.6

81.2 ± 13.9

91.8 ± 23.2**##

 Uric acid (μmol/L)

325.1 ± 60.6

470.6 ± 55.0**

536.2 ± 131.4**##

 Triglyceride (mmol/L)

1.1 ± 0.4

2.3 ± 1.2**

3.1 ± 2.1**

 Cholesterol (mmol/L)

4.7 ± 0.8

5.2 ± 0.8**

5.4 ± 1.0**

 HDL-cholesterol (mmol/L)

1.4 ± 0.3

1.1 ± 0.2**

1.3 ± 0.3##

 LDL-cholesterol (mmol/L)

2.7 ± 0.5

3.2 ± 0.7**

3.0 ± 0.6*

  1. Data are presented as mean ± SD except where stated otherwise
  2. HUA hyperuricemia, BMI body mass index, DBP diastolic blood pressure, SBP systolic blood pressure, ALT alanine aminotransferase, AST aspartate aminotransferase, HDL high-density lipoprotein, LDL low-density lipoprotein
  3. *p < 0.05, **p < 0.01, compared to control; #p < 0.05, ##p < 0.01, compared to the HUA group