Table 2 Summary of significantly changed metabolites in the HUA and gout group
Metabolites | Changes in HUA (vs control) | Changes in gout (vs control) | Changes in gout (vs HUA) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Trend | r a | p b | Trend | r a | p b | Trend | r a | p b | |
VLDL | ↑ | 0.71 | 0.00 | ↑ | 0.61 | 0.00 | ↑ | 0.61 | 0.00 |
Isoleucine | ↑ | 0.86 | 0.00 | ↑ | 0.72 | 0.00 | – | – | – |
Leucine | ↑ | 0.83 | 0.00 | ↑ | 0.71 | 0.00 | – | – | – |
Lipid | ↑ | 0.68 | 0.00 | ↑ | 0.72 | 0.00 | ↑ | 0.63 | 0.00 |
Lactate | ↑ | 0.70 | 0.00 | – | – | – | – | – | – |
Alanine | ↑ | 0.77 | 0.00 | – | – | – | – | – | – |
Lysine | ↑ | 0.76 | 0.00 | – | – | – | – | – | – |
Glutamine | – | – | – | ↑ | 0.60 | 0.00 | – | – | – |
Methionine | – | – | – | ↑ | 0.67 | 0.00 | – | – | – |
Acetone | ↑ | 0.64 | 0.00 | ↑ | 0.63 | 0.00 | ↑ | 0.65 | 0.00 |
Glutamate | ↑ | 0.69 | 0.00 | – | – | – | – | – | – |
Citrate | – | – | – | ↑ | 0.68 | 0.00 | ↑ | 0.65 | 0.00 |
Aspartate | – | – | – | ↑ | 0.73 | 0.00 | ↑ | 0.63 | 0.00 |
Creatinine | ↑ | 0.63 | 0.00 | ↑ | 0.65 | 0.00 | – | – | – |
β-Glucose | ↑ | 0.65 | 0.00 | ↑ | 0.70 | 0.00 | ↑ | 0.65 | 0.00 |
α-Glucose | ↑ | 0.63 | 0.00 | ↑ | 0.68 | 0.00 | ↑ | 0.66 | 0.00 |
Threonine | ↑ | 0.65 | 0.00 | ↑ | 0.60 | 0.00 | – | – | – |
Triglycerides | ↑ | 0.70 | 0.00 | ↑ | 0.61 | 0.00 | – | – | – |
Unsaturated lipids | ↑ | 0.67 | 0.00 | ↑ | 0.63 | 0.00 | – | – | – |
Tyrosine | ↑ | 0.75 | 0.00 | – | – | – | – | – | – |
Phenylalanine | – | – | – | ↑ | 0.63 | 0.00 | – | – | – |