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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Transcription factor motif enrichment in whole transcriptome analysis identifies STAT4 and BCL6 as the most prominent binding motif in systemic juvenile idiopathic arthritis

Fig. 4

Expression of HLA-DRB1 in active (AD) versus inactive (ID) systemic juvenile idiopathic arthritis using reverse transcription PCR. Left graph, fold change (n-fold) of longitudinal samples before and after treatment with anakinra, with inactive disease set to level 1 (*p < 0.05). Right graph, delta cycle threshold (ΔCt) values (relative expression values related to ribosomal protein L (RPL)) in active systemic disease (cohorts I and II), active polyarticular disease, and inactive disease/remission, and controls (all cohort II)

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