From: Gout and the risk of myocardial infarction in older adults: a study of Medicare recipients
 | Multivariable-adjusteda model 1 | Multivariable-adjusteda model 2 | Multivariable-adjusteda model 3 | |||
---|---|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | HR (95% CI) | p value | |
Age (years) | ||||||
 65 to < 75 | Ref |  | Ref |  | Ref |  |
 75 to < 85 | 1.62 (1.56, 1.68) | < 0.0001 | 1.60 (1.54, 1.66) | < 0.0001 | 1.55 (1.49, 1.61) | < 0.0001 |
 ≥ 85 | 2.51 (2.39, 2.64) | < 0.0001 | 2.52 (2.39, 2.64) | < 0.0001 | 2.47 (2.35, 2.60) | < 0.0001 |
Gender | ||||||
 Male | Ref |  | Ref |  | Ref |  |
 Female | 0.75 (0.73, 0.78) | < 0.0001 | 0.74 (0.72, 0.77) | < 0.0001 | 0.76 (0.74, 0.79) | < 0.0001 |
Race | ||||||
 White | Ref |  | Ref |  | Ref |  |
 Black | 1.00 (0.94, 1.06) | 0.97 | 1.05 (0.99, 1.11) | 0.10 | 0.95 (0.90, 1.01) | 0.11 |
 Other | 0.93 (0.86, 1.00) | 0.038 | 0.97 (0.90, 1.04) | 0.35 | 0.89 (0.83, 0.96) | 0.002 |
Charlson–Romano score, per unit change | 1.21 (1.21, 1.22) | < 0.0001 | N/A |  | N/A |  |
Charlson–Romano comorbidity score, N (%) | ||||||
 0 | N/A |  | Ref |  | N/A |  |
 1 |  |  | 2.20 (2.08, 2.33) | < 0.0001 |  |  |
 ≥ 2 |  |  | 3.11 (2.99, 3.23) | < 0.0001 |  |  |
Gout | 2.08 (1.95, 2.21) | < 0.0001 | 2.14 (2.01, 2.27) | < 0.0001 | 1.79 (1.68, 1.90) | < 0.0001 |