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Table 3 Association of gout with MI, in predefined subgroup analyses

From: Gout and the risk of myocardial infarction in older adults: a study of Medicare recipients

 

Multivariable-adjusted model 1

Multivariable-adjusted model 1

Multivariable-adjusted model 1

HR (95% CI)

p value

HR (95% CI)

p value

HR (95% CI)

p value

 

Black

White

Other race

Gout

2.49 (2.10, 2.96)

< 0.0001

2.02 (1.89, 2.16)

< 0.0001

2.05 (1.59, 2.65)

< 0.0001

 

Female

Male

  

Gout

2.13 (1.94, 2.35)

< 0.0001

2.04 (1.89, 2.21)

< 0.0001

  
 

Age 65–75 years

Age 75–85 years

Age > 85 years

Gout

2.09 (1.90, 2.31)

< 0.0001

1.89 (1.73, 2.08)

< 0.0001

2.50 (2.15, 2.91)

< 0.0001

 

No hypertension

 

Hypertension

   

Gout

3.00 (2.65, 3.40)

< 0.0001

1.73 (1.61, 1.85)

< 0.0001

  
 

No diabetes

 

Diabetes

   

Gout

2.35 (2.17, 2.55)

< 0.0001

1.64 (1.49, 1.80)

< 0.0001

  
 

No hyperlipidemia

 

Hyperlipidemia

   

Gout

2.45 (2.24, 2.69)

< 0.0001

1.74 (1.60, 1.90)

< 0.0001

  
 

No heart failure

 

Heart failure

   

Gout

2.20 (2.04, 2.36)

< 0.0001

1.73 (1.55, 1.93)

< 0.0001

  
 

No CAD

 

CAD

   

Gout

2.18 (2.01, 2.37)

< 0.0001

1.74 (1.59, 1.91)

< 0.0001

  
  1. Race × gout, p = 0.10
  2. Age × gout, p < 0.05
  3. Gender × gout, p = 0.017
  4. Hypertension × gout, p < 0.0001
  5. Diabetes × gout, p < 0.0001
  6. Heart failure × gout, p < 0.0001
  7. Hyperlipidemia × gout, p < 0.0001
  8. CAD × gout, p < 0.0001
  9. Bold data represent significant HRs with p < 0.05
  10. HR hazard ratio, CI confidence interval, CAD coronary artery disease