Fig. 2From: From supernatants to cytokines: a personal view on the early history of IL-1, IL-1Ra, TNF and its inhibitor in rheumatologySequential pathways from TL to MF and to synovial fibroblast activation [7]. MCF mononuclear cell factor, MΦ monocyte-macrophages, PGE2 prostaglandin E2, Fc Fragment crystallizable of immunoglobulin, ag antigenBack to article page