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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients

Fig. 4

Chymase in synovial fluid of patients with RA and OA and its cleavage of chemerin. a Chymase levels in synovial fluid of patients with OA (n = 10) and RA (n = 8) determined using human chymase ELISA as described under “Methods”. b chem163S-15mer incubated with 10 nM chymase for 30 min before analysis by HPLC. Product concentration calculated by interpolation from standard curve, and velocities of product generation determined. OA osteoarthritis, RA rheumatoid arthritis

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