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Table 2 Association between the use of histamine H1-receptor antagonists and prevalence of radiographic knee OA

From: H1-antihistamines are associated with lower prevalence of radiographic knee osteoarthritis: a cross-sectional analysis of the Osteoarthritis Initiative data

 

Non-adjusted models

Adjusted models

OR

95% CI

P value

OR

95% CI

P value

Radiographic knee OA, defined as KL ≥ 2 with JSN

0.78

0.63 to 0.95

0.014

0.77

0.62 to 0.96

0.02

Radiographic knee OA, defined as KL ≥ 2

0.81

0.67 to 0.99

0.041

0.75

0.62 to 0.93

0.008

  1. Note. The models were adjusted for BMI, race, age, gender, Physical Activity scale for the elderly (PASE), history of knee surgery, family history of knee OA, smoking status, education, and Subcohort assignment. OR – odds ratio, CI – confidence interval