From: Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis
Nr-axSpA (n = 101) | Control subjects (n = 50) | p Value | |
---|---|---|---|
Demographic characteristics | |||
Female sex, n (%) | 42 (41.6) | 20 (40) | 0.852 |
Age, yr | 45.0 (15.0) | 44.76 (26.0) | 0.917 |
Height, m | 1.74 (0.1) | 1.74 (0.1) | 0.997 |
Weight, kg | 81.1 (21.5) | 76.0 (18.5) | 0.054 |
Body mass index, kg/m2 | 26.3 (6.5) | 23.8 (5.2) | 0.118 |
Current or previous smoking, n (%) | 38 (37.6) | 11 (24.4) | 0.119 |
Disease-specific characteristics | |||
HLA-B27 positivity, n (%) | 75 (75.0) | – | – |
Duration of disease, yr | 6.5 (9.0) | – | – |
Disease remission, n (%) | 15 (14.9) | – | – |
ASDAS-CRP, units | 2.1 (1.4) | – | – |
BASDAI, units | 3.5 (3.6) | – | – |
C-reactive protein, mg/L | 6.2 (4.0) | – | – |
ESR, mm | 12.7 (10.5) | – | – |
BASFI, units | 2.9 (3.8) | – | – |
BASMI, units | 1.1 (2) | – | – |
Peripheral arthritis, n (%) | 35 (34.7) | – | – |
Dactylitis, n (%) | 2 (2.0) | – | – |
Enthesitis, n (%) | 17 (16.8) | – | – |
MASES, units | 1.1 (1) | – | – |
Psoriasis, n (%) | 13 (12.9) | – | – |
Uveitis, n (%) | 8 (7.9) | – | – |
Inflammatory bowel disease, n (%) | 7 (6.9) | – | – |
Low trauma fracture, n (%) | 7 (6.9) | – | – |
25(OH)vitamin D3, ng/ml | 32.4 (16.3) | – | – |
Treatment modalities | |||
Current biologic therapya, n (%) | 59 (58.4) | – | – |
Duration of biologic therapy, yr | 2.0 (4.0) | ||
Current DMARD therapyb, n (%) | 28 (27.7) | – | – |
NSAID, n (%) | 68 (67.3) | – | – |
NSAID daily, n (%) | 22 (21.8) | – | – |
NSAID on demand, n (%) | 46 (45.5) | – | – |
Prednisolone ≥ 5 mg > 3 monthsc, n (%) | 32 (31.7) | – | – |
Calcium substitution, n (%) | 8 (7.9) | – | – |
25(OH)vitamin D3 substitution, n (%) | 26 (25.7) | – | – |
Antiresorptive treatment, n (%) | 5 (5.0) | – | – |