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Table 4 Associations between the presence of four potentially pathogenic MT-CO3 alleles and clinical phenotypes in gout

From: Next-generation sequencing profiling of mitochondrial genomes in gout

Variables

Potentially pathogenic MT-CO3 alleles

P

+

–

Number (percentage)

4 (7.69)

48 (92.31)

 

Age (years; mean ± SD)

50.00 ± 12.99

51.73 ± 10.77

0.798

Uric acid (mg/dl; mean ± SD)

6.60 ± 2.07

7.71 ± 1.63

0.236

BMI (kg/m2; mean ± SD)

23.87 ± 2.09

26.70 ± 3.74

0.118

Diabetes mellitus (n (%))

1 (25.00)

3 (6.25)

0.281

Fasting glucose (mg/dl; mean ± SD)

98.50 ± 14.89

99.90 ± 19.31

0.973

Total cholesterol (mg/dl; mean ± SD)

192.20 ± 45.17

191.00 ± 39.92

0.693

HDL (mg/dl; mean ± SD)

61.00 ± 12.41

47.17 ± 12.60

0.034

LDL (mg/dl; mean ± SD)

119.30 ± 34.81

119.50 ± 38.81

0.918

Triglycerides (mg/dl; mean ± SD)

137.80 ± 86.89

159.10 ± 100.30

0.706

  1. Abbreviations: SD standard deviation, BMI body mass index, HDL high-density lipoproteins, LDL low-density lipoproteins. P: Estimated by Mann-Whitney U or exact test