Skip to main content

Table 1 Demographic and clinical characteristics of study subjects

From: Functional intraepithelial lymphocyte changes in inflammatory bowel disease and spondyloarthritis have disease specific correlations with intestinal microbiota

 

Controls (N = 15)

CD (N = 10)

UC (N = 7)

axSpA (N = 6)

p value

Age in years

48.4 (9.7)

40.5 (15.2)

39.2 (12.4)

34.4 (3.3)

0.06

Female

9 (60%)

7 (70%)

3 (43%)

1 (17%)

0.18

Non-Hispanic white

15 (100%)

9 (90%)

6 (86%)

6 (100%)

0.29

Former smoker

4 (27%)

5 (50%)

1 (14%)

3 (50%)

0.34

Family history of autoimmunity

6 (40%)

3 (30%)

1 (14%)

2 (33%)

0.53

Disease duration in months

127.5 (107.9)

171.7 (153.9)

78.5 (58.1)

0.36

HLA-B27 positivity

0

0

1 (14%)

5 (83%)

0.0001 a

WBC (109 cells/L)

7.2 (2.2)

6.6 (2.2)

5.5 (3.2)

9.5 (2.3)

0.04

Absolute lymphocytes (109 cells/L)

1.9 (0.1)

1.7 (0.2)

0.9 (0.1)

2.6 (0.3)

0.004

CRP (mg/L)

2.5 (2.5)

4.2 (3.0)

1.7 (1.7)

5.6 (12.5)

0.5

TNF inhibitor usage

5 (50%)

0 (0%)

5 (83%)

< 0.01

Prednisone usage

2 (20%)

0 (0%)

1 (17%)

0.5

Harvey Bradshaw Index

1.9 (0.526)

 

Simple Clinical Colitis Activity Index

0.857 (0.553)

Bath AS Disease Activity Index

3.96 (1.01)

  1. Data are mean (SD) or number (%); p value is based on Fisher’s exact test for categorical variables and on one-way analysis of variance for continuous variables. aBold text indicates significant p-values
  2. HC healthy controls, CD Crohn’s disease, UC ulcerative colitis, axSpA axial spondyloarthritis, CRP C-reactive protein, AS ankylosing spondylitis