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Table 1 Demographic and clinical characteristics of study subjects

From: Functional intraepithelial lymphocyte changes in inflammatory bowel disease and spondyloarthritis have disease specific correlations with intestinal microbiota

  Controls (N = 15) CD (N = 10) UC (N = 7) axSpA (N = 6) p value
Age in years 48.4 (9.7) 40.5 (15.2) 39.2 (12.4) 34.4 (3.3) 0.06
Female 9 (60%) 7 (70%) 3 (43%) 1 (17%) 0.18
Non-Hispanic white 15 (100%) 9 (90%) 6 (86%) 6 (100%) 0.29
Former smoker 4 (27%) 5 (50%) 1 (14%) 3 (50%) 0.34
Family history of autoimmunity 6 (40%) 3 (30%) 1 (14%) 2 (33%) 0.53
Disease duration in months 127.5 (107.9) 171.7 (153.9) 78.5 (58.1) 0.36
HLA-B27 positivity 0 0 1 (14%) 5 (83%) 0.0001 a
WBC (109 cells/L) 7.2 (2.2) 6.6 (2.2) 5.5 (3.2) 9.5 (2.3) 0.04
Absolute lymphocytes (109 cells/L) 1.9 (0.1) 1.7 (0.2) 0.9 (0.1) 2.6 (0.3) 0.004
CRP (mg/L) 2.5 (2.5) 4.2 (3.0) 1.7 (1.7) 5.6 (12.5) 0.5
TNF inhibitor usage 5 (50%) 0 (0%) 5 (83%) < 0.01
Prednisone usage 2 (20%) 0 (0%) 1 (17%) 0.5
Harvey Bradshaw Index 1.9 (0.526)  
Simple Clinical Colitis Activity Index 0.857 (0.553)
Bath AS Disease Activity Index 3.96 (1.01)
  1. Data are mean (SD) or number (%); p value is based on Fisher’s exact test for categorical variables and on one-way analysis of variance for continuous variables. aBold text indicates significant p-values
  2. HC healthy controls, CD Crohn’s disease, UC ulcerative colitis, axSpA axial spondyloarthritis, CRP C-reactive protein, AS ankylosing spondylitis