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Table 4 Test properties of radiograph for detection of structural lesions consistent with sacroiliitis on MRI

From: Radiographs in screening for sacroiliitis in children: what is the value?

 

Rater 1

Rater 2

Rater 3

Rater 4

Rater 5

Percent (95% CI)

 Sensitivity

25.0 (7.3–52.4)

33.3 (7.5–70.1)

75.0 (42.8–94.5)

53.8 (25.1–80.8)

68.4 (43.4–87.4)

 Specificity

90.9 (78.3–97.5)

90.2 (78.6–96.7)

62.5 (47.4–76.0)

78.7 (64.3–89.3)

70.7 (54.5–83.9)

 PPV

50.0 (15.7–84.3)

37.5 (8.5–75.5)

33.3 (16.5–54.0)

41.2 (18.4–67.1)

52.0 (31.3–72.2)

 NPV

76.9 (63.2–87.5)

88.5 (76.6–95.6)

90.9 (75.7–98.1)

86.0 (72.1–94.7)

82.9 (66.4–93.4)

Frequency (%)

 Radiograph–a

  Radiograph–/MRI–

40 (76.9)

46 (88.5)

30 (90.9)

37 (86)

29 (82.9)

  Radiograph–/MRI+

12 (23.1)

6 (11.5)

3 (9.1)

6 (14)

6 (17.1)

 Radiograph+a

  Radiograph+/MRI–

4 (50)

5 (62.5)

18 (66.7)

10 (58.8)

12 (48)

  Radiograph+/MRI+

4 (50)

3 (37.5)

9 (33.3)

7 (41.2)

13 (52)

  1. Kappa value interpretations: ≤ 0.40 poor agreement, 0.41–0.59 fair agreement, 0.60–0.74 good agreement, and ≥ 0.75 excellent agreement [21]. For sensitivity, specificity, PPV, and NPV calculations, positive radiograph defined as global impression of sacroiliitis (yes) and reference standard was MRI global impression of structural lesions consistent with sacroiliitis (yes)
  2. CI confidence interval, MRI magnetic resonance imaging, NPV negative predictive value, PPV positive predictive value
  3. aMRI and radiograph + or – defined as global impression of sacroiliitis (yes/no)
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Arthritis Research & Therapy

ISSN: 1478-6362

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